eyeCare - Keep it running, always...

You can configure eyeCare to be running all the time, so that it can remind you to take break, even when you are not browsing. Below video demonstrates this.

Please note that your browser should be allowed to run background apps for this functionality to work. At the moment of writing this, for Google's Chrome browser, the background app mode can be enable at the "System" section, as shown in the below screenshot.